Imophoron
Tackling the biggest challenges around vaccine development
Funding stage: Seed
What Imophoron does
Imophoron is developing a new and unique platform to produce vaccines that are stable at temperatures of up to 50°C, tackling the cold chain problem of the vaccine industry. Imophoron also intend to deliver vaccines intranasally, providing an over-the-counter nasal spray alternative to injections for common viruses such as the flu.
Currently vaccines need to be stored on ice, some at temperatures as low as -80°C (for example, in the case of RNA-based COVID vaccines). This is not easy to maintain, and 25% of vaccines degrade by the time they reach their destination after being exposed to higher temperatures.*
The cold chain problems result in a significant reduction in the shelf-life and efficiency of the vaccine, huge cost increases, and distribution limitations in areas with hotter climates, all of which impact access for patients in countries facing critical issues due to lack of vaccinations.
* Iata, How to become CEIV Pharma Certified, 2020
Why we like it
The COVID pandemic has not only highlighted some of the biggest inefficiencies across the global healthcare system, but also shone a light on how poorly the world’s governments and healthcare systems are set-up to respond to biological threats, infectious disease and pandemics. The WHO and other non-profit organisations (such as The Gates Foundation) highlight that governments, investors and pharma pour money into vaccine development when a new pandemic or epidemic arrives, however this interest soon plummets as the epidemic or pandemic is over.
This demonstrates the need for investment and research into platform technologies that can accelerate the vaccine development and approval process, and develop vaccine technologies which can be tailored rather than starting from scratch every time. Imophoron’s disruptive platform technology aims to achieve exactly this.